EZ Blister is a laboratory blister packaging machine ideal for clinical trials.

The Sepha EZ Blister is a table top blister packaging machine, ideal for packaging tablets, capsules, ampoules, sachets, pouches and other products. The machine has a range of options that can be selected to tailor and format the machine to meet individual commercial, manufacturing and technological requirements.

The EZ Blister offers a 3-in-1 manufacturing process for low volume blister packaging including forming, sealing and perforating/cutting.

  1. Forming

Through either thermoforming or coldforming trays are formed to exact product requirements.

  1. Sealing

The formed trays are sealed with pre-cut pieces of the selected lidding material using knurled or flat heat sealing plates. Product traceability can be achieved by choosing the option of code embossing.

  1. Perforating & Cutting

The sealed trays are cut and perforated using a precision die cutter.

The table top blister packaging machine can help departments involved with clinical trials, stability studies, specialist drugs or packaging development as it’s designed to create small batches. The EZ Blister eliminates the need to interrupt busy schedules of Production departments, saving time and money. It also gives more freedom to plan and budget smaller projects as and when required.


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  • Customizable to individual commercial and manufacturing requirements
  • Easy setup via HMI and minimal training required
  • Compact space saving bench top design
  • Precision engineered knurled or heat sealing plates
  • Forms from pre-cut pieces of forming material
  • Modified Atmosphere Packaging (MAP) function available as an optional extra.
  • Cold forming capability
  • Tool-less changeover of format parts in less than 2 minutes
  • All machine parts either grade 304 stainless steel, anodized aluminium or PTFE
  • Perforated cutting tools (optional)
  • Teflon coated forming plates
  • Operating speed of approx. 200 cycles per hour for any single operation
  • Pack Dimensions
    Max. format area: 180mm x 120mm / Max. thermoform depth: 14mm* / Max. coldform depth: 12mm* (*Dependent on material type and cavity profile)
  • Operation
    Max. format area: 180mm x 120mm / Max. thermoform depth: 14mm* / Max. coldform depth: 12mm* (*Dependent on material type and cavity profile)
  • Construction
    Stainless Steel (Grade 304)
  • User Interface
    Touchscreen HMI, hand operated regulators, push buttons
  • Controls
    Temperature: 0 - 200°C settable ±1 °C / Pressure: 0.2 – 0.6 MPa (Force: 6.3 – 18.8 kN) / Timers: 0 – 99.9 sec settable ±0.1 sec / Counter: 0 - 9999 cycles
  • Utilities
    Electrical: Min. 110V Single phase, 15A, Min. 230V Single phase, 6.5A / Air: Min. 250L/min at 0.6Mpa [ISO8573-1:2010 CLASS 2]
  • Operating Speed
    Approx. 200 cycles per hour for any single operation
  • Tooling Changeover
    2-3 minutes
  • Tooling Warm-up
    Approx. 10-15 minutes
  • Machine Dimensions
    715mm (L) x 655mm (W) x 555mm (H)
  • Weight
    Machine: 138kg / Tooling: 12kg / Shipping: 200kg (inc. tooling)
  • Warranty
    Supplied with a 12-month warranty. (Extended warranties are available for additional support).

EZ Blister is ideal for producing small batches of high quality blister packs in:

Pharmaceutical Research and Development laboratories

  • Clinical trials
  • Stability studies
  • Package development
  • Marketing samples

Pharmaceutical production and packaging departments

Low volumes which may not normally be economic on high speed fully automatic lines can be turned around quickly on EZ Blister, e.g. packing small batches of specialist drugs.

More control for R&D labs

  • Bring your blister packing in-house instead of booking time on production lines or outsourcing to a third party – minimises delays, allowing your new drug product to get to market sooner
  • Every day saved in the R&D lab is a day of extra profits in the marketplace

Flexible pack design

  • Blister pack using a variety of materials, novel shapes, sizes or perforations – allows the full range of possibilities to be explored for pack development in the R&D lab
  • Offers increased flexibility to contract packers

High quality blisters

  • Reproducible, production quality packaging
  • Fast & easy set-up – no specialist knowledge is required to operate EZ Blister so there is no need for an engineer to be present

Compact, portable design

Table top design for convenient blister packaging

Reduce R&D time

  • Sepha can design your new blister packs. This is especially useful for customers who conduct clinical trials. We can advise them how to rationalise the number of different tools needed, even if the lab needs to package many different products
  • Fast turnaround to tool-up for new products – 2-3 weeks for thermoform and cold-form tooling, faster than outsourcing small batches to a contract packer

More economical for batches up to 20,000 units

  • Fully cGMP compliant, so it is quick to clean – requires 5 minutes
  • Fast 2-minute changeover – reduces down-time between production batches

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